CIRc-014 [Ligand Id: 14493] activity data from GtoPdb

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  • cyclin A1 in Human [GtoPdb: 3351] [UniProtKB: P78396]
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  • cyclin B1 in Human [GtoPdb: 3352] [UniProtKB: P14635]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
cyclin A1 in Human [GtoPdb: 3351] [UniProtKB: P78396]
GtoPdb Binding affinity for CDK2/Cyclin A1 complex, determined by fluorescence polarization - 7.3 pIC50 50 nM IC50 J Med Chem (2026) 69: 5441-5460 [PMID:41721763]
cyclin B1 in Human [GtoPdb: 3352] [UniProtKB: P14635]
GtoPdb Binding affinity for CDK1/Cyclin B1 complex, determined by fluorescence polarization - 7.7 pIC50 <20 nM IC50 J Med Chem (2026) 69: 5441-5460 [PMID:41721763]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.