ChEMBL ligand: CHEMBL300004
GPR35/G-protein coupled receptor 35 in Human [ChEMBL: CHEMBL1293267] [GtoPdb: 102] [UniProtKB: Q9HC97] There should be some charts here, you may need to enable JavaScript!
motilin receptor/Motilin receptor in Human [ChEMBL: CHEMBL2203] [GtoPdb: 297] [UniProtKB: O43193] Motilin receptor in Rabbit [ChEMBL: CHEMBL5306] [UniProtKB: A5A4K8] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
GPR35/G-protein coupled receptor 35 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1293267] [GtoPdb: 102] [UniProtKB: Q9HC97]
ChEMBL	GPCR PRESTO-Tango dose-response in agonist mode with target: GPR35	F	5	pEC50	>10000	nM	EC50	EUbOPEN Chemogenomics Library - GPCR Dose-Respose
motilin receptor/Motilin receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2203] [GtoPdb: 297] [UniProtKB: O43193]
GtoPdb	-	-	6.3	pIC50	-	-	-	J Pharmacol Exp Ther (2005) 313: 1397-405 [PMID:15764739]
ChEMBL	Compound was tested for in vitro motilin receptor binding affinity after treatment with hydrochloric acid solution (pH 2.5)	B	6.65	pIC50	223.87	nM	IC50	Bioorg Med Chem Lett (1995) 5: 835-838
ChEMBL	Compound was tested for in vitro motilin receptor binding affinity	B	8.47	pIC50	3.39	nM	IC50	Bioorg Med Chem Lett (1995) 5: 835-838
Motilin receptor in Rabbit (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5306] [UniProtKB: A5A4K8]
ChEMBL	Concentration required for in vitro acid stability with hydrochloric acid solution (pH 2.5 ) at room temperature for 2 hr by assaying the solution for motilin receptor binding	B	6.65	pIC50	223.87	nM	IC50	Bioorg Med Chem Lett (1994) 4: 1347-1352
ChEMBL	Concentration required for in vitro motilin receptor binding, expressed as negative logarithm of IC50	B	8.47	pIC50	3.39	nM	IC50	Bioorg Med Chem Lett (1994) 4: 1347-1352

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]