GPR84 antagonist 42E2 [Ligand Id: 14448] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| GPR84 in Human [GtoPdb: 120] [UniProtKB: Q9NQS5] | ||||||||
| GtoPdb | Determined in a competition binding study, dispalcing orthosteric antagonist [3H]140 | - | 8.16 | pKi | 6.92 | nM | Ki | J Med Chem (2026) 69: 7945-7965 [PMID:41870364] |
| GtoPdb | Determined in a [35S]GTPγS incorporation (functional) assay, in Flp-ln TREx HEK293 cells stably expressing hGPR84 treated with agonist ZQ-16 (2-HTP) | - | 6.6 | pIC50 | 251 | nM | IC50 | J Med Chem (2026) 69: 7945-7965 [PMID:41870364] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
