NVP-BHG712 isomer [Ligand Id: 14228] activity data from GtoPdb

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  • EPH receptor A2 in Human [GtoPdb: 1822] [UniProtKB: P29317]
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  • EPH receptor B4 in Human [GtoPdb: 1833] [UniProtKB: P54760]
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  • discoidin domain receptor tyrosine kinase 1 in Human [GtoPdb: 1843] [UniProtKB: Q08345]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
EPH receptor A2 in Human [GtoPdb: 1822] [UniProtKB: P29317]
GtoPdb - - 7.14 pKd 73 nM Kd ChemMedChem (2018) 13: 1629-1633 [PMID:29928781]
EPH receptor B4 in Human [GtoPdb: 1833] [UniProtKB: P54760]
GtoPdb - - 6.85 pKd 142 nM Kd ChemMedChem (2018) 13: 1629-1633 [PMID:29928781]
discoidin domain receptor tyrosine kinase 1 in Human [GtoPdb: 1843] [UniProtKB: Q08345]
GtoPdb Binding affinity determined in a Kinobeads assay - 7.07 pKd 85.4 nM Kd ChemMedChem (2018) 13: 1629-1633 [PMID:29928781]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.