L-serine-O-phosphate [Ligand Id: 1411] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL284377 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| mGlu4 receptor in Human [GtoPdb: 292] [UniProtKB: Q14833] | ||||||||
| GtoPdb | - | - | 5.9 | pEC50 | 1420 | nM | EC50 | Brain Res Mol Brain Res (1998) 53: 88-97 [PMID:9473604] |
| mGlu4 receptor in Rat [GtoPdb: 292] [UniProtKB: P31423] | ||||||||
| GtoPdb | - | - | 6.2 | pIC50 | - | - | - |
J Neurosci (1993) 13: 1372-8 [PMID:8463825]; Neuropharmacology (1997) 36: 21-30 [PMID:9144638]; Br J Pharmacol (1995) 116: 3279-87 [PMID:8719808]; J Biol Chem (1999) 274: 10008-13 [PMID:10187777]; Neuroreport (1993) 4: 1099-101 [PMID:8106006] |
| mGlu6 receptor in Human [GtoPdb: 294] [UniProtKB: O15303] | ||||||||
| GtoPdb | - | - | 6.4 | pEC50 | - | - | - | Neuropharmacology (1997) 36: 145-52 [PMID:9144651] |
| mGlu7 receptor in Human [GtoPdb: 295] [UniProtKB: Q14831] | ||||||||
| GtoPdb | - | - | 4.4 | pKi | - | - | - | Naunyn Schmiedebergs Arch Pharmacol (2000) 362: 546-54 [PMID:11138847] |
| GtoPdb | - | - | 4.5 | pEC50 | 31000 | nM | EC50 | Brain Res Mol Brain Res (1998) 53: 88-97 [PMID:9473604] |
| mGlu8 receptor in Human [GtoPdb: 296] [UniProtKB: O00222] | ||||||||
| GtoPdb | - | - | 7.2 | pIC50 | - | - | - |
Brain Res Mol Brain Res (1998) 53: 88-97 [PMID:9473604]; Brain Res Mol Brain Res (1999) 67: 201-10 [PMID:10216218] |
ChEMBL data shown on this page come from version 35:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
