AC1115 [Ligand Id: 13927] activity data from GtoPdb

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  • cathepsin L in Human [GtoPdb: 2351] [UniProtKB: P07711]
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  • CoV 3C-like (main) protease in SARS-CoV-2 [GtoPdb: 3111]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
cathepsin L in Human [GtoPdb: 2351] [UniProtKB: P07711]
GtoPdb - - 10.22 pIC50 0.06 nM IC50 Med (2024) 5: 42-61.e23 [PMID:38181791]
CoV 3C-like (main) protease in SARS-CoV-2 [GtoPdb: 3111]
GtoPdb Inhibition of SARS-CoV-2 Mpro from the Omicron strain - 7.85 pIC50 14.27 nM IC50 Med (2024) 5: 42-61.e23 [PMID:38181791]
GtoPdb Inhibition of SARS-CoV-2 Mpro from wild type strain WA-1 - 8.61 pIC50 2.44 nM IC50 Med (2024) 5: 42-61.e23 [PMID:38181791]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.