nipocalimab [Ligand Id: 13876] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| Fc fragment of IgG receptor and transporter in Human [GtoPdb: 2985] [UniProtKB: P55899] | ||||||||
| GtoPdb | Binding dissociation constant determined at pH 7.6 (extracellular compartment) | - | 10.36 | pKd | 0.04 | nM | Kd | Clin Pharmacol Ther (2019) 105: 1031-1039 [PMID:30402880] |
| GtoPdb | Binding dissociation constant determined at pH 6.0 (endosomal compartment) | - | 10.54 | pKd | 0.03 | nM | Kd | Clin Pharmacol Ther (2019) 105: 1031-1039 [PMID:30402880] |
| GtoPdb | Measuring inhibition of IgG binding to FcRn | - | 8.52 | pIC50 | 3 | nM | IC50 | Clin Pharmacol Ther (2019) 105: 1031-1039 [PMID:30402880] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
