serplulimab [Ligand Id: 13796] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| programmed cell death 1 (CD279) in Human [GtoPdb: 2760] [UniProtKB: Q15116] | ||||||||
| GtoPdb | Measuring binding affinity for cell-surface expressed PD-1 | - | 8.43 | pKd | 3.7 | nM | Kd | PLoS One (2021) 16: e0257972 [PMID:34972111] |
| GtoPdb | Binding affinity for monomeric human PD-1 determined by biolayer interferometry (BLI) assay | - | 8.62 | pKd | 2.42 | nM | Kd | PLoS One (2021) 16: e0257972 [PMID:34972111] |
| GtoPdb | Potency for antagonism of PD-1/PD-L2 binding | - | 8.19 | pIC50 | 6.46 | nM | IC50 | PLoS One (2021) 16: e0257972 [PMID:34972111] |
| GtoPdb | Potency for antagonism of PD-1/PD-L1 binding | - | 8.36 | pIC50 | 4.36 | nM | IC50 | PLoS One (2021) 16: e0257972 [PMID:34972111] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
