stapokibart [Ligand Id: 13785] activity data from GtoPdb

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  • Interleukin-4 receptor subunit α in Monkey [GtoPdb: 1697]
  • Interleukin-4 receptor subunit α in Human [GtoPdb: 1697] [UniProtKB: P24394]
  • Interleukin-4 receptor subunit α in Rat [GtoPdb: 1697] [UniProtKB: Q63257]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Interleukin-4 receptor subunit α in Monkey [GtoPdb: 1697]
GtoPdb Binding affinity determined by SPR - 8.82 pKd 1.5 nM Kd iScience (2024) 27: 110721 [PMID:39262798]
Interleukin-4 receptor subunit α in Human [GtoPdb: 1697] [UniProtKB: P24394]
GtoPdb Binding affinity determined by SPR - 9.6 pKd 0.25 nM Kd iScience (2024) 27: 110721 [PMID:39262798]
GtoPdb Antagonism of IL-4 interaction with IL-4R&alpha determined by competitive ELISA - 9.4 pIC50 0.4 nM IC50 iScience (2024) 27: 110721 [PMID:39262798]
Interleukin-4 receptor subunit α in Rat [GtoPdb: 1697] [UniProtKB: Q63257]
GtoPdb Binding affinity determined by SPR - 8.56 pKd 2.75 nM Kd iScience (2024) 27: 110721 [PMID:39262798]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.