cagrilintide [Ligand Id: 13768] activity data from GtoPdb

Click here for a description of the charts and data table

Please tell us if you are using this feature and what you think!

  • CT receptor in Human [GtoPdb: 43] [UniProtKB: P30988]
There should be some charts here, you may need to enable JavaScript!
  • AMY3 receptor in Human [GtoPdb: 46]
There should be some charts here, you may need to enable JavaScript!
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
CT receptor in Human [GtoPdb: 43] [UniProtKB: P30988]
GtoPdb Determined by displacement of 125I-Calcitonin binding to CT receptor in a radioligand binding assay - 9.64 pIC50 0.23 nM IC50 J Med Chem (2021) 64: 11183-11194 [PMID:34288673]
GtoPdb Measuring activation of CT receptor in a cAMP-responsive element luciferase reporter assay - 9.54 pEC50 0.29 nM EC50 J Med Chem (2021) 64: 11183-11194 [PMID:34288673]
AMY3 receptor in Human [GtoPdb: 46]
GtoPdb Determined by displacement of 125I-rat amylin binding to AMY3R in a radioligand binding assay - 9.77 pIC50 0.17 nM IC50 J Med Chem (2021) 64: 11183-11194 [PMID:34288673]
GtoPdb Receptor activation in a cAMP assay - 9.46 pEC50 0.35 nM EC50 J Med Chem (2021) 64: 11183-11194 [PMID:34288673]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.