perzebertinib [Ligand Id: 13741] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| epidermal growth factor receptor in Human [GtoPdb: 1797] [UniProtKB: P00533] | ||||||||
| GtoPdb | Inhibition of wt EGFR phosphorylation in NCI H838 cells | - | 7.92 | pIC50 | 12 | nM | IC50 | WO2020057511A1. Quinazoline derivatives as antitumor agents (2020) |
| erb-b2 receptor tyrosine kinase 2 in Human [GtoPdb: 2019] [UniProtKB: P04626] | ||||||||
| GtoPdb | Inhibition of HER2 phosphorylation in BT474 cells | - | 8.02 | pIC50 | 9.5 | nM | IC50 | WO2020057511A1. Quinazoline derivatives as antitumor agents (2020) |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
