AZ-PRMT5i-1 [Ligand Id: 13638] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| protein arginine methyltransferase 5 in Human [GtoPdb: 1256] [UniProtKB: O14744] | ||||||||
| GtoPdb | Inhibitory activity in HCT-116 colorectal cancer cells with MTAP gene deletion, measuring the symmetric dimethyl arginine (SDMA) level as a measure of PRMT5 activity. | - | 8.26 | pIC50 | 5.5 | nM | IC50 | J Med Chem (2024) 67: 13604-13638 [PMID:39080842] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
