BAY2413555 [Ligand Id: 13637] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| M2 receptor in Human [GtoPdb: 14] [UniProtKB: P08172] | ||||||||
| GtoPdb | Binding affinity for for [3H]-BAY2413555 determined in an radioligand equilibrium dissociation binding assay. | - | 7.77 | pKd | 17 | nM | Kd | J Med Chem (2024) 67: 19165-19187 [PMID:39463278] |
| GtoPdb | Determined in a functional M2-GIRK assay, measuring potentiation of acetylcholine (EC20) mediated M2R activation; Positive cooperativity >1 | - | 8.7 | pEC50 | 2 | nM | EC50 | J Med Chem (2024) 67: 19165-19187 [PMID:39463278] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
