mosperafenib [Ligand Id: 13500] activity data from GtoPdb
Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
|
There should be some charts here, you may need to enable JavaScript!
|
|
There should be some charts here, you may need to enable JavaScript!
|
| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| B-Raf proto-oncogene, serine/threonine kinase in Human [GtoPdb: 1943] [UniProtKB: P15056] | ||||||||
| GtoPdb | Affinity for WT BRAF | - | 8.05 | pKd | 8.9 | nM | Kd | WO2021116050A1. New braf inhibitors as paradox breakers (2021) |
| GtoPdb | Affinity for BRAFV600E | - | 8.35 | pKd | 4.5 | nM | Kd | WO2021116050A1. New braf inhibitors as paradox breakers (2021) |
| Raf-1 proto-oncogene, serine/threonine kinase in Human [GtoPdb: 2184] [UniProtKB: P04049] | ||||||||
| GtoPdb | Affinity for WT CRAF | - | 8.05 | pKd | 8.9 | nM | Kd | WO2021116050A1. New braf inhibitors as paradox breakers (2021) |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
