XPC-7224 [Ligand Id: 13390] activity data from GtoPdb

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  • Nav1.6 in Human [GtoPdb: 583] [UniProtKB: Q9UQD0]
  • Nav1.6 in Mouse [GtoPdb: 583] [UniProtKB: Q9WTU3]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Nav1.6 in Human [GtoPdb: 583] [UniProtKB: Q9UQD0]
GtoPdb Concentration responses were measured at holding potentials where channels were maintained at fully inactivated potentials. - 7.11 pIC50 78 nM IC50 ACS Chem Neurosci (2024) 15: 1169-1184 [PMID:38359277]
Nav1.6 in Mouse [GtoPdb: 583] [UniProtKB: Q9WTU3]
GtoPdb Concentration responses were measured at holding potentials where channels were maintained at fully inactivated potentials. - 6.89 pIC50 130 nM IC50 ACS Chem Neurosci (2024) 15: 1169-1184 [PMID:38359277]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.