AZD8421 [Ligand Id: 13385] activity data from GtoPdb

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  • cyclin dependent kinase 2 in Human [GtoPdb: 1973] [UniProtKB: P24941]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
cyclin dependent kinase 2 in Human [GtoPdb: 1973] [UniProtKB: P24941]
GtoPdb Measuring inhibition of endogenous substrate phosphorylation in a cellular assay. - 7.24 pIC50 58 nM IC50 Cancer Research (2024) 84:
GtoPdb Determined in a nanoBRET assay measuring cellular target engagement. - 8.05 pIC50 9 nM IC50 Cancer Research (2024) 84:

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.