daraxonrasib [Ligand Id: 13368] activity data from GtoPdb

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  • KRAS in Human [GtoPdb: 2824] [UniProtKB: P01116]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
KRAS in Human [GtoPdb: 2824] [UniProtKB: P01116]
GtoPdb Binding affinity of the RMC-6236/CypA binary complex for mutated KRASG12C - 6.44 pKd 364 nM Kd Cancer Discov (2024) 14: 994-1017 [PMID:38593348]
GtoPdb Binding affinity of the RMC-6236/CypA binary complex for WT human KRAS - 6.81 pKd 154 nM Kd Cancer Discov (2024) 14: 994-1017 [PMID:38593348]
GtoPdb Binding affinity of the RMC-6236/CypA binary complex for mutated KRASG12V - 6.88 pKd 131 nM Kd Cancer Discov (2024) 14: 994-1017 [PMID:38593348]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.