VVD-133214 [Ligand Id: 13353] activity data from GtoPdb

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  • WRN RecQ like helicase in Human [GtoPdb: 3259] [UniProtKB: Q14191]
  • WRN RecQ like helicase in Mouse [GtoPdb: 3259] [UniProtKB: O09053]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
WRN RecQ like helicase in Human [GtoPdb: 3259] [UniProtKB: Q14191]
GtoPdb Inhibition of the DNA unwinding activity of hWRN(519-1227) in the presence of ATP - 6.89 pIC50 130 nM IC50 Nature (2024) 629: 435-442 [PMID:38658751]
WRN RecQ like helicase in Mouse [GtoPdb: 3259] [UniProtKB: O09053]
GtoPdb Inhibition of the DNA unwinding activity of mWRN(486-1232) in the presence of ATP - 7.03 pIC50 93 nM IC50 Nature (2024) 629: 435-442 [PMID:38658751]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.