compound 17 [PMID: 38477582] [Ligand Id: 13346] activity data from GtoPdb

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  • phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha in Human [GtoPdb: 2153] [UniProtKB: P42336]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha in Human [GtoPdb: 2153] [UniProtKB: P42336]
GtoPdb Inhibition of AKT phosphorylation in T47D breast cancer cells harbouring PI3KαH1047R, using a AlphaLISA assay - 9 pIC50 1 nM IC50 J Med Chem (2024) 67: 4936-4949 [PMID:38477582]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.