GLPG2737 [Ligand Id: 13290] activity data from GtoPdb
Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
|
|
| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| CFTR in Human [GtoPdb: 707] [UniProtKB: P13569] | ||||||||
| GtoPdb | Determined in a Cell Surface Expression Horseradish Peroxidase (CSE-HRP) assay | - | 6.16 | pEC50 | 695 | nM | EC50 | J Med Chem (2024) 67: 5216-5232 [PMID:38527911] |
| GtoPdb | In the presence of potentiator GLPG1837 and corrector GLPG2222- determined in a Transepithelial Clamp Circuit (TECC) electrophysiological assay | - | 7.15 | pEC50 | 71 | nM | EC50 | J Med Chem (2024) 67: 5216-5232 [PMID:38527911] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
