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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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GDNF family receptor alpha like in Human [GtoPdb: 2977] [UniProtKB: Q6UXV0] | ||||||||
GtoPdb | Binding affinity for GFRAL receptor construct D2-D3-ECD-HIS | - | 8.51 | pKd | 3.1 | nM | Kd | Cell Metab (2023) 35: 274-286.e10 [PMID:36630958] |
GtoPdb | In vitro functional activity of LY3463251 | - | 7.26 | pEC50 | 54.7 | nM | EC50 | Cell Metab (2023) 35: 274-286.e10 [PMID:36630958] |
GDNF family receptor alpha like in Mouse [GtoPdb: 2977] [UniProtKB: Q6SJE0] | ||||||||
GtoPdb | In vitro functional activity of LY3463251 | - | 6.87 | pEC50 | 136.2 | nM | EC50 | Cell Metab (2023) 35: 274-286.e10 [PMID:36630958] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.