ChEMBL ligand: CHEMBL4162752 (Ddo-3055)
egl-9 family hypoxia inducible factor 1/Egl nine homolog 1 in Human [ChEMBL: CHEMBL5697] [GtoPdb: 2833] [UniProtKB: Q9GZT9] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
egl-9 family hypoxia inducible factor 1/Egl nine homolog 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5697] [GtoPdb: 2833] [UniProtKB: Q9GZT9]
ChEMBL	Inhibition of HIF-PHD2 (unknown origin) by fluorescence polarization assay	B	4.86	pIC50	13700	nM	IC50	J Med Chem (2018) 61: 6964-6982 [PMID:29712435]
GtoPdb	-	-	7.19	pIC50	64.2	nM	IC50	J Med Chem (2020) 63: 10045-10060 [PMID:32787144]
ChEMBL	Inhibition of FITC-HIF1alpha (556 to 574 residues) binding to PHD2 (181 to 426 residues) (unknown origin) by fluorescence polarization assay	B	7.19	pIC50	64.2	nM	IC50	J Med Chem (2020) 63: 10045-10060 [PMID:32787144]
ChEMBL	Binding affinity to full length PHD2 (181 to 426 residues) (unknown origin) by fluorescence polarization assay	B	7.81	pIC50	15.62	nM	IC50	J Med Chem (2023) 66: 8545-8563 [PMID:37367818]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]