(R)-YNT-3708 [Ligand Id: 12606] activity data from GtoPdb

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  • OX1 receptor in Human [GtoPdb: 321] [UniProtKB: O43613]
Created with Highcharts 10.3.3ValuesChart context menuOX1 receptorpKd HumanpKi HumanpIC50 HumanpEC50 Human0246810Highcharts.com
  • OX2 receptor in Human [GtoPdb: 322] [UniProtKB: O43614]
Created with Highcharts 10.3.3ValuesChart context menuOX2 receptorpKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
OX1 receptor in Human [GtoPdb: 321] [UniProtKB: O43613]
GtoPdb Determined in a calcium mobilization assay - 8.11 pEC50 7.74 nM EC50 J Med Chem (2023) 66: 5453-5464 [PMID:37043436]
OX2 receptor in Human [GtoPdb: 322] [UniProtKB: O43614]
GtoPdb Determined in a calcium mobilization assay - 6.77 pEC50 168 nM EC50 J Med Chem (2023) 66: 5453-5464 [PMID:37043436]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.