compound 52 [PMID: 36749735] [Ligand Id: 12412] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| epidermal growth factor receptor in Human [GtoPdb: 1797] [UniProtKB: P00533] | ||||||||
| GtoPdb | Inhibition of WT EGFR enzymatic activity | - | 7.6 | pIC50 | 25 | nM | IC50 | J Med Chem (2023) 66: 2566-2588 [PMID:36749735] |
| GtoPdb | Inhibition of EGFRL858R/T790M enzyme activity | - | 7.82 | pIC50 | 15 | nM | IC50 | J Med Chem (2023) 66: 2566-2588 [PMID:36749735] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
