compound 27 [PMID: 36449304] [Ligand Id: 12314] activity data from GtoPdb

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  • CTP synthase 1 in Human [GtoPdb: 3215] [UniProtKB: P17812]
  • CTP synthase 1 in Mouse [GtoPdb: 3215] [UniProtKB: Q922Y4]
  • CTP synthase 1 in Rat [GtoPdb: 3215]
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  • CTP synthase 2 in Human [GtoPdb: 3216] [UniProtKB: Q9NRF8]
  • CTP synthase 2 in Mouse [GtoPdb: 3216] [UniProtKB: P70303]
  • CTP synthase 2 in Rat [GtoPdb: 3216] [UniProtKB: Q5U2N0]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
CTP synthase 1 in Human [GtoPdb: 3215] [UniProtKB: P17812]
GtoPdb - - 7.49 pIC50 32 nM IC50 J Med Chem (2022) 65: 16640-16650 [PMID:36449304]
CTP synthase 1 in Mouse [GtoPdb: 3215] [UniProtKB: Q922Y4]
GtoPdb - - 7.59 pIC50 26 nM IC50 J Med Chem (2022) 65: 16640-16650 [PMID:36449304]
CTP synthase 1 in Rat [GtoPdb: 3215]
GtoPdb - - 7.57 pIC50 27 nM IC50 J Med Chem (2022) 65: 16640-16650 [PMID:36449304]
CTP synthase 2 in Human [GtoPdb: 3216] [UniProtKB: Q9NRF8]
GtoPdb - - 7.74 pIC50 18 nM IC50 J Med Chem (2022) 65: 16640-16650 [PMID:36449304]
CTP synthase 2 in Mouse [GtoPdb: 3216] [UniProtKB: P70303]
GtoPdb - - 7.48 pIC50 33 nM IC50 J Med Chem (2022) 65: 16640-16650 [PMID:36449304]
CTP synthase 2 in Rat [GtoPdb: 3216] [UniProtKB: Q5U2N0]
GtoPdb - - 7.64 pIC50 23 nM IC50 J Med Chem (2022) 65: 16640-16650 [PMID:36449304]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.