GNE-064 [Ligand Id: 12206] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| polybromo 1 in Human [GtoPdb: 2738] [UniProtKB: Q86U86] | ||||||||
| GtoPdb | Inhibitory potency at the 5th bromodomain of PBRM1, determined by BromoScan assay | - | 7.74 | pIC50 | 18 | nM | IC50 | J Med Chem (2022) 65: 11177-11186 [PMID:35930799] |
| SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 in Human [GtoPdb: 2739] [UniProtKB: P51531] | ||||||||
| GtoPdb | Potency determined by BromoScan assay | - | 7.8 | pIC50 | 16 | nM | IC50 | J Med Chem (2022) 65: 11177-11186 [PMID:35930799] |
| SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 in Human [GtoPdb: 2740] [UniProtKB: P51532] | ||||||||
| GtoPdb | Potency determined by TR-FRET assay | - | 7.46 | pIC50 | 35 | nM | IC50 | J Med Chem (2022) 65: 11177-11186 [PMID:35930799] |
| GtoPdb | Potency determined by BromoScan assay | - | 8 | pIC50 | 10 | nM | IC50 | J Med Chem (2022) 65: 11177-11186 [PMID:35930799] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
