MAGLi 432 [Ligand Id: 12123] activity data from GtoPdb

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  • monoacylglycerol lipase in Human [GtoPdb: 1399] [UniProtKB: Q99685]
  • monoacylglycerol lipase in Mouse [GtoPdb: 1399] [UniProtKB: O35678]
Created with Highcharts 10.3.3ValuesChart context menumonoacylglycerol lipasepKd HumanpKi HumanpIC50 HumanpEC50 HumanpKd MousepKi MousepIC50 MousepEC50 Mouse0246810Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
monoacylglycerol lipase in Human [GtoPdb: 1399] [UniProtKB: Q99685]
GtoPdb - - 8.38 pIC50 4.2 nM IC50 WO2019134985A1. Octahydropyrido[1,2-alpha]pyrazines as magl inhibitors (2019)
monoacylglycerol lipase in Mouse [GtoPdb: 1399] [UniProtKB: O35678]
GtoPdb - - 8.51 pIC50 3.1 nM IC50 WO2019134985A1. Octahydropyrido[1,2-alpha]pyrazines as magl inhibitors (2019)

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.