ChEMBL ligand: CHEMBL350775 (Biricodar)
FKBP prolyl isomerase 1A/FK506-binding protein 1A in Human [ChEMBL: CHEMBL1902] [GtoPdb: 2609] [UniProtKB: P62942] There should be some charts here, you may need to enable JavaScript!
FKBP prolyl isomerase 4/FK506 binding protein 4 in Human [ChEMBL: CHEMBL4050] [GtoPdb: 3176] [UniProtKB: Q02790] There should be some charts here, you may need to enable JavaScript!
ABCC1/Multidrug resistance-associated protein 1 in Human [ChEMBL: CHEMBL3004] [GtoPdb: 779] [UniProtKB: P33527] There should be some charts here, you may need to enable JavaScript!
FKBP prolyl isomerase 5/Peptidyl-prolyl cis-trans isomerase FKBP5 in Human [ChEMBL: CHEMBL2052031] [GtoPdb: 3175] [UniProtKB: Q13451] There should be some charts here, you may need to enable JavaScript!
P-glycoprotein 1 in Mouse [ChEMBL: CHEMBL3467] [UniProtKB: P06795] There should be some charts here, you may need to enable JavaScript!
ABCB1 in Human [GtoPdb: 768] [UniProtKB: P08183] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
FKBP prolyl isomerase 1A/FK506-binding protein 1A in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1902] [GtoPdb: 2609] [UniProtKB: P62942]
ChEMBL	Binding affinity to FKBP12 by fluorescence polarization assay	B	7.77	pIC50	17	nM	IC50	J Med Chem (2012) 55: 4114-4122 [PMID:22455444]
FKBP prolyl isomerase 4/FK506 binding protein 4 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4050] [GtoPdb: 3176] [UniProtKB: Q02790]
ChEMBL	Binding affinity to FKBP52 FK1 domain by fluorescence polarization assay	B	5.13	pIC50	7370	nM	IC50	J Med Chem (2012) 55: 4114-4122 [PMID:22455444]
ABCC1/Multidrug resistance-associated protein 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3004] [GtoPdb: 779] [UniProtKB: P33527]
ChEMBL	Inhibition of multidrug resistance associated protein type 1 (MRP1) assayed by an accumulation assay in COR.L23/R cells	F	5.29	pIC50	5180	nM	IC50	Bioorg Med Chem Lett (2002) 12: 571-574 [PMID:11844674]
GtoPdb	-	-	5.29	pIC50	5180	nM	IC50	Bioorg Med Chem Lett (2002) 12: 571-4 [PMID:11844674]
FKBP prolyl isomerase 5/Peptidyl-prolyl cis-trans isomerase FKBP5 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2052031] [GtoPdb: 3175] [UniProtKB: Q13451]
ChEMBL	Binding affinity to FKBP51 FK1 domain by fluorescence polarization assay	B	5.07	pIC50	8520	nM	IC50	J Med Chem (2012) 55: 4114-4122 [PMID:22455444]
P-glycoprotein 1 in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3467] [UniProtKB: P06795]
ChEMBL	Inhibitory activity against P-glycoprotein (Pgp) using accumulation assay for Pgp expressing EMT6/AR1.0 cells.	F	5.3	pIC50	5000	nM	IC50	Bioorg Med Chem Lett (2002) 12: 571-574 [PMID:11844674]
ABCB1 in Human [GtoPdb: 768] [UniProtKB: P08183]
GtoPdb	-	-	5.3	pIC50	5000	nM	IC50	Bioorg Med Chem Lett (2002) 12: 571-4 [PMID:11844674]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]