[3H]alniditan [Ligand Id: 117] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL88240 (Alniditan) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| 5-HT1A receptor/Serotonin 1a (5-HT1a) receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL214] [GtoPdb: 1] [UniProtKB: P08908] | ||||||||
| ChEMBL | Ability to bind to 5-hydroxytryptamine 1A receptor from cloned human expressed in Ha7 cells | B | 8.3 | pIC50 | 5.01 | nM | IC50 | Bioorg Med Chem Lett (1995) 5: 2649-2654 |
| 5-HT1D receptor/Serotonin 1d (5-HT1d) receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1983] [GtoPdb: 3] [UniProtKB: P28221] | ||||||||
| GtoPdb | - | - | 8.92 | pKd | 1.2 | nM | Kd | Br J Pharmacol (1998) 123: 1655-65 [PMID:9605573] |
| ChEMBL | Ability to bind to 5-hydroxytryptamine 1D receptor of calf substantia nigra | B | 8.6 | pIC50 | 2.51 | nM | IC50 | Bioorg Med Chem Lett (1995) 5: 2649-2654 |
| 5-HT1B receptor in Human [GtoPdb: 2] [UniProtKB: P28222] | ||||||||
| GtoPdb | - | - | 9 | pKd | 1 | nM | Kd | Br J Pharmacol (1998) 123: 1655-65 [PMID:9605573] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
