nirmatrelvir [Ligand Id: 11503] activity data from GtoPdb

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  • CoV 3C-like (main) protease in SARS-CoV-2 [GtoPdb: 3111]
Created with Highcharts 10.3.3ValuesChart context menuCoV 3C-like (main) proteasepKd SARS-CoV-2pKi SARS-CoV-2pIC50 SARS-CoV-2pEC50 SARS-CoV-2024681012Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
CoV 3C-like (main) protease in SARS-CoV-2 [GtoPdb: 3111]
GtoPdb Determined in vitro, in a TR-FRET enzyme assay - 9.57 pKi 0.27 nM Ki Science (2021) 374: 1586-1593 [PMID:34726479]
GtoPdb - - 7.48 pIC50 33 nM IC50 J Am Chem Soc (2022) 144: 2905-2920 [PMID:35142215]
GtoPdb - - 7.72 pIC50 19 nM IC50

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.