selepressin [Ligand Id: 11454] activity data from GtoPdb and ChEMBL
Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
| ChEMBL ligand: CHEMBL1817709 (Fe-202158, FE 202158, FE-202158, FE202158, Selepresina, Selepressin, Selepressine) |
|---|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| OT receptor/Oxytocin receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2049] [GtoPdb: 369] [UniProtKB: P30559] | ||||||||
| ChEMBL | Agonist activity at human OT receptor expressed in CHO-K1 cells by luciferase reporter gene assay | F | 5.96 | pEC50 | 1100 | nM | EC50 | J Med Chem (2011) 54: 4388-4398 [PMID:21688787] |
| ChEMBL | Agonist activity at human OT receptor expressed in CHO-K1 cells by luciferase reporter gene assay | F | 8.62 | pEC50 | 2.4 | nM | EC50 | J Med Chem (2011) 54: 4388-4398 [PMID:21688787] |
| V1A receptor/Vasopressin V1a receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1889] [GtoPdb: 366] [UniProtKB: P37288] | ||||||||
| ChEMBL | Agonist activity at recombinant human vasopressin V1a receptor expressed in HEK293 cells by luciferase reporter gene assay | F | 8.62 | pEC50 | 2.4 | nM | EC50 | J Med Chem (2011) 54: 4388-4398 [PMID:21688787] |
| ChEMBL | Agonist activity at recombinant human vasopressin V1a receptor expressed in HEK293 cells by luciferase reporter gene assay | F | 8.62 | pEC50 | 2.4 | nM | EC50 | J Med Chem (2011) 54: 4388-4398 [PMID:21688787] |
| GtoPdb | - | - | 8.62 | pEC50 | 2.4 | nM | EC50 | J Pharmacol Exp Ther (2011) 337: 786-96 [PMID:21411496] |
| V1A receptor/Vasopressin V1a receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2868] [GtoPdb: 366] [UniProtKB: P30560] | ||||||||
| ChEMBL | Agonist activity at recombinant rat vasopressin V1a receptor expressed in HEK293 cells by luciferase reporter gene assay | F | 9.26 | pEC50 | 0.55 | nM | EC50 | J Med Chem (2011) 54: 4388-4398 [PMID:21688787] |
| ChEMBL | Agonist activity at recombinant rat vasopressin V1a receptor expressed in HEK293 cells by luciferase reporter gene assay | F | 9.26 | pEC50 | 0.55 | nM | EC50 | J Med Chem (2011) 54: 4388-4398 [PMID:21688787] |
| V1B receptor/Vasopressin V1b receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1921] [GtoPdb: 367] [UniProtKB: P47901] | ||||||||
| ChEMBL | Agonist activity at recombinant human vasopressin V1b receptor expressed in Flp-In-293 cells by luciferase reporter gene assay | F | 6.47 | pEC50 | 340 | nM | EC50 | J Med Chem (2011) 54: 4388-4398 [PMID:21688787] |
| ChEMBL | Agonist activity at recombinant human vasopressin V1b receptor expressed in Flp-In-293 cells by luciferase reporter gene assay | F | 6.47 | pEC50 | 338.84 | nM | EC50 | J Med Chem (2011) 54: 4388-4398 [PMID:21688787] |
| V2 receptor/Vasopressin V2 receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1790] [GtoPdb: 368] [UniProtKB: P30518] | ||||||||
| ChEMBL | Agonist activity at recombinant human vasopressin V2 receptor expressed in HEK293 cells by luciferase reporter gene assay | F | 5.57 | pEC50 | 2700 | nM | EC50 | J Med Chem (2011) 54: 4388-4398 [PMID:21688787] |
| ChEMBL | Agonist activity at recombinant human vasopressin V2 receptor expressed in HEK293 cells by luciferase reporter gene assay | F | 5.58 | pEC50 | 2630.27 | nM | EC50 | J Med Chem (2011) 54: 4388-4398 [PMID:21688787] |
ChEMBL data shown on this page come from version 34:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
