AM-37 [Ligand Id: 11262] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL3590072 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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| FPR3/Formyl peptide receptor-related sequence 1 in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3407315] [GtoPdb: 224] [UniProtKB: O08790] | ||||||||
| ChEMBL | Agonist activity at FPR2 in BALB/c mouse assessed as stimulation of Ca2+ influx measured every 5 secs for 240 secs by FLIPR assay | F | 5.68 | pEC50 | 2100 | nM | EC50 | Bioorg Med Chem (2015) 23: 3913-3924 [PMID:25549897] |
| BB2 receptor in Human [GtoPdb: 39] [UniProtKB: P30550] | ||||||||
| GtoPdb | Measuring inhibition of specific [125]I-BA1 binding to hBB2 receptor in vitro. | - | 5.85 | pKi | 1400 | nM | Ki | Front Endocrinol (Lausanne) (2017) 8: 176 [PMID:28785244] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
