DSM502 [Ligand Id: 11219] activity data from GtoPdb

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  • Plasmodium falciparum dihydroorotate dehydrogenase in Plasmodium falciparum [GtoPdb: 2949]
  • Plasmodium falciparum dihydroorotate dehydrogenase in Plasmodium vivax [GtoPdb: 2949]
  • Plasmodium falciparum dihydroorotate dehydrogenase in Plasmodium falciparum 3D7 [GtoPdb: 2949] [UniProtKB: Q08210]
  • Plasmodium falciparum dihydroorotate dehydrogenase in Plasmodium falciparum Dd2 [GtoPdb: 2949]
  • This target only has 0 pki data point
1 _lig_chart_1 Plasmodium falciparum dihydroorotate dehydrogenase Plasmodium falciparumPlasmodium vivaxPlasmodium falciparum 3D7Plasmodium falciparum Dd2
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Plasmodium falciparum dihydroorotate dehydrogenase in Plasmodium falciparum [GtoPdb: 2949]
GtoPdb Steady-state kinetic analysis. - 7.7 pIC50 20 nM IC50 J. Med. Chem. (2020) 63: 4929-4956 [PMID:32248693]
Plasmodium falciparum dihydroorotate dehydrogenase in Plasmodium vivax [GtoPdb: 2949]
GtoPdb Steady-state kinetic analysis. - 7.85 pIC50 14 nM IC50 J. Med. Chem. (2020) 63: 4929-4956 [PMID:32248693]
Plasmodium falciparum dihydroorotate dehydrogenase in Plasmodium falciparum 3D7 [GtoPdb: 2949] [UniProtKB: Q08210]
GtoPdb Parasite growth inhibition assay - 7.85 pEC50 14 nM EC50 J. Med. Chem. (2020) 63: 4929-4956 [PMID:32248693]
Plasmodium falciparum dihydroorotate dehydrogenase in Plasmodium falciparum Dd2 [GtoPdb: 2949]
GtoPdb Parasite growth inhibition assay - 7.8 pEC50 16 nM EC50 J. Med. Chem. (2020) 63: 4929-4956 [PMID:32248693]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.