DSM502 [Ligand Id: 11219] activity data from GtoPdb
Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
There should be some charts here, you may need to enable JavaScript!
|
| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| Plasmodium falciparum dihydroorotate dehydrogenase in Plasmodium falciparum [GtoPdb: 2949] | ||||||||
| GtoPdb | Steady-state kinetic analysis. | - | 7.7 | pIC50 | 20 | nM | IC50 | J Med Chem (2020) 63: 4929-4956 [PMID:32248693] |
| Plasmodium falciparum dihydroorotate dehydrogenase in Plasmodium vivax [GtoPdb: 2949] | ||||||||
| GtoPdb | Steady-state kinetic analysis. | - | 7.85 | pIC50 | 14 | nM | IC50 | J Med Chem (2020) 63: 4929-4956 [PMID:32248693] |
| Plasmodium falciparum dihydroorotate dehydrogenase in Plasmodium falciparum 3D7 [GtoPdb: 2949] [UniProtKB: Q08210] | ||||||||
| GtoPdb | Parasite growth inhibition assay | - | 7.85 | pEC50 | 14 | nM | EC50 | J Med Chem (2020) 63: 4929-4956 [PMID:32248693] |
| Plasmodium falciparum dihydroorotate dehydrogenase in Plasmodium falciparum Dd2 [GtoPdb: 2949] | ||||||||
| GtoPdb | Parasite growth inhibition assay | - | 7.8 | pEC50 | 16 | nM | EC50 | J Med Chem (2020) 63: 4929-4956 [PMID:32248693] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License