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ChEMBL ligand: CHEMBL4633246 |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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Plasmodium falciparum dihydroorotate dehydrogenase in Plasmodium falciparum [GtoPdb: 2949] | ||||||||
GtoPdb | Steady-state kinetic analysis. | - | 7.7 | pIC50 | 20 | nM | IC50 | J Med Chem (2020) 63: 4929-4956 [PMID:32248693] |
Plasmodium falciparum dihydroorotate dehydrogenase in Plasmodium vivax [GtoPdb: 2949] | ||||||||
GtoPdb | Steady-state kinetic analysis. | - | 7.85 | pIC50 | 14 | nM | IC50 | J Med Chem (2020) 63: 4929-4956 [PMID:32248693] |
Plasmodium falciparum dihydroorotate dehydrogenase in Plasmodium falciparum 3D7 [GtoPdb: 2949] [UniProtKB: Q08210] | ||||||||
GtoPdb | Parasite growth inhibition assay | - | 7.85 | pEC50 | 14 | nM | EC50 | J Med Chem (2020) 63: 4929-4956 [PMID:32248693] |
Plasmodium falciparum dihydroorotate dehydrogenase in Plasmodium falciparum Dd2 [GtoPdb: 2949] | ||||||||
GtoPdb | Parasite growth inhibition assay | - | 7.8 | pEC50 | 16 | nM | EC50 | J Med Chem (2020) 63: 4929-4956 [PMID:32248693] |
ChEMBL data shown on this page come from version 28:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]