obatoclax [Ligand Id: 11086] activity data from GtoPdb

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  • BCL2 apoptosis regulator in Human [GtoPdb: 2844] [UniProtKB: P10415]
Created with Highcharts 10.3.3ValuesChart context menuBCL2 apoptosis regulatorpKd HumanpKi HumanpIC50 HumanpEC50 Human01234567Highcharts.com
  • Bcl-2-like 1 in Human [GtoPdb: 2845] [UniProtKB: Q07817]
Created with Highcharts 10.3.3ValuesChart context menuBcl-2-like 1pKd HumanpKi HumanpIC50 HumanpEC50 Human0123456Highcharts.com
  • MCL1 apoptosis regulator, BCL2 family member in Human [GtoPdb: 2847] [UniProtKB: Q07820]
Created with Highcharts 10.3.3ValuesChart context menuMCL1 apoptosis regulator, BCL2 family memberpKd HumanpKi HumanpIC50 HumanpEC50 Human0123456Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
BCL2 apoptosis regulator in Human [GtoPdb: 2844] [UniProtKB: P10415]
GtoPdb In vitro antagonism determined in a fluorescence polarisation assay. - 5.96 pKi 1100 nM Ki Eur J Med Chem (2018) 146: 471-482 [PMID:29407973]
Bcl-2-like 1 in Human [GtoPdb: 2845] [UniProtKB: Q07817]
GtoPdb In vitro antagonism determined in a fluorescence polarisation assay. - 5.33 pKi 4690 nM Ki Eur J Med Chem (2018) 146: 471-482 [PMID:29407973]
MCL1 apoptosis regulator, BCL2 family member in Human [GtoPdb: 2847] [UniProtKB: Q07820]
GtoPdb In vitro antagonism determined in a fluorescence polarisation assay. - 5.54 pKi 2900 nM Ki Eur J Med Chem (2018) 146: 471-482 [PMID:29407973]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.