BAY1125976 [Ligand Id: 10908] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| AKT serine/threonine kinase 1 in Human [GtoPdb: 1479] [UniProtKB: P31749] | ||||||||
| GtoPdb | Biochemical inhibition in a TR-FRET assay using full-length human AKT1 and biotinylated peptide biotin-Ahx-KKLNRTLSFAEPG as substrate. | - | 8.28 | pIC50 | 5.2 | nM | IC50 | WO2012136776A1. Imidazopyridazines as Akt kinase inhibitors (2012) |
| AKT serine/threonine kinase 2 in Human [GtoPdb: 1480] [UniProtKB: P31751] | ||||||||
| GtoPdb | Biochemical inhibition in a TR-FRET assay using full-length human AKT2 and biotinylated peptide biotin-Ahx-KKLNRTLSFAEPG as substrate. | - | 7.74 | pIC50 | 18 | nM | IC50 | WO2012136776A1. Imidazopyridazines as Akt kinase inhibitors (2012) |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
