WJYK50 [Ligand Id: 10639] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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| sphingomyelin phosphodiesterase 1 in Human [GtoPdb: 2514] [UniProtKB: P17405] | ||||||||
| GtoPdb | Inhibition of recombinant human sphingomyelin phosphodiesterase 1 (ASM). | - | 6.05 | pIC50 | 890 | nM | IC50 | J Med Chem (2020) 63: 961-974 [PMID:31944697] |
| GtoPdb | Inhibition of ASM-induced ceramide production in an extract from human hepatocellular carcinoma (Huh 7) cells. | - | 6.32 | pIC50 | 480 | nM | IC50 | Eur J Med Chem (2018) 151: 389-400 [PMID:29649738] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
