ChEMBL ligand: CHEMBL14227 (Butanoic acid)
FFA3 receptor/Free fatty acid receptor 3 in Human [ChEMBL: CHEMBL5201] [GtoPdb: 227] [UniProtKB: O14843] There should be some charts here, you may need to enable JavaScript!
histone deacetylase 1/Histone deacetylase 1 in Human [ChEMBL: CHEMBL325] [GtoPdb: 2658] [UniProtKB: Q13547] There should be some charts here, you may need to enable JavaScript!
histone deacetylase 2/Histone deacetylase 2 in Human [ChEMBL: CHEMBL1937] [GtoPdb: 2616] [UniProtKB: Q92769] There should be some charts here, you may need to enable JavaScript!
histone deacetylase 3/Histone deacetylase 3 in Human [ChEMBL: CHEMBL1829] [GtoPdb: 2617] [UniProtKB: O15379] There should be some charts here, you may need to enable JavaScript!
histone deacetylase 8/Histone deacetylase 8 in Human [ChEMBL: CHEMBL3192] [GtoPdb: 2619] [UniProtKB: Q9BY41] There should be some charts here, you may need to enable JavaScript!
OAT6/Solute carrier family 22 member 20 in Mouse [ChEMBL: CHEMBL5269] [GtoPdb: 1037] [UniProtKB: Q80UJ1] There should be some charts here, you may need to enable JavaScript!
FFA2 receptor in Human [GtoPdb: 226] [UniProtKB: O15552] There should be some charts here, you may need to enable JavaScript!
HCA2 receptor in Human [GtoPdb: 312] [UniProtKB: Q8TDS4] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
FFA3 receptor/Free fatty acid receptor 3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5201] [GtoPdb: 227] [UniProtKB: O14843]
GtoPdb	-	-	4.9	pEC50	-	-	-	J Biol Chem (2003) 278: 11312-9 [PMID:12496283]; J Biol Chem (2003) 278: 25481-9 [PMID:12711604]; Proc Natl Acad Sci USA (2004) 101: 1045-50 [PMID:14722361]; J Biol Chem (2011) 286: 10628-40 [PMID:21220428]
ChEMBL	Agonist activity at human GPCR41 transfected in HEK293 cells assessed as [35S]GTPgammaS binding by scintillation counting method	F	4.92	pEC50	12000	nM	EC50	J Med Chem (2018) 61: 47-61 [PMID:28745893]
histone deacetylase 1/Histone deacetylase 1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL325] [GtoPdb: 2658] [UniProtKB: Q13547]
ChEMBL	Inhibition of human recombinant HDAC1	B	4.8	pIC50	16000	nM	IC50	ACS Med. Chem. Lett. (2011) 2: 39-42 [PMID:21874153]
GtoPdb	-	-	4.8	pIC50	16000	nM	IC50	ACS Med Chem Lett (2010) 2: 39-42 [PMID:21874153]
histone deacetylase 2/Histone deacetylase 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1937] [GtoPdb: 2616] [UniProtKB: Q92769]
GtoPdb	-	-	4.92	pIC50	12000	nM	IC50	ACS Med Chem Lett (2010) 2: 39-42 [PMID:21874153]
ChEMBL	Inhibition of human recombinant HDAC2	B	4.92	pIC50	12000	nM	IC50	ACS Med. Chem. Lett. (2011) 2: 39-42 [PMID:21874153]
histone deacetylase 3/Histone deacetylase 3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1829] [GtoPdb: 2617] [UniProtKB: O15379]
ChEMBL	Inhibition of human recombinant HDAC3	B	5.05	pIC50	9000	nM	IC50	ACS Med. Chem. Lett. (2011) 2: 39-42 [PMID:21874153]
GtoPdb	-	-	5.05	pIC50	9000	nM	IC50	ACS Med Chem Lett (2010) 2: 39-42 [PMID:21874153]
histone deacetylase 8/Histone deacetylase 8 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3192] [GtoPdb: 2619] [UniProtKB: Q9BY41]
GtoPdb	-	-	4.82	pIC50	15000	nM	IC50	ACS Med Chem Lett (2010) 2: 39-42 [PMID:21874153]
ChEMBL	Inhibition of human recombinant HDAC8	B	4.82	pIC50	15000	nM	IC50	ACS Med. Chem. Lett. (2011) 2: 39-42 [PMID:21874153]
OAT6/Solute carrier family 22 member 20 in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5269] [GtoPdb: 1037] [UniProtKB: Q80UJ1]
ChEMBL	Inhibition of mouse Oat6-mediated [3H]ES uptake in Xenopus oocytes after 1 hr	B	4.09	pKi	82000	nM	Ki	J. Biol. Chem. (2007) 282: 23841-23853 [PMID:17553798]
ChEMBL	Inhibition of mouse Oat6-mediated [3H]ES uptake in Xenopus oocytes after 1 hr	B	4.09	pKi	81283.05	nM	Ki	J. Biol. Chem. (2007) 282: 23841-23853 [PMID:17553798]
FFA2 receptor in Human [GtoPdb: 226] [UniProtKB: O15552]
GtoPdb	-	-	4.6	pEC50	-	-	-	J Biol Chem (2003) 278: 11312-9 [PMID:12496283]; Biochem Biophys Res Commun (2003) 303: 1047-52 [PMID:12684041]; J Biol Chem (2003) 278: 25481-9 [PMID:12711604]; J Biol Chem (2011) 286: 10628-40 [PMID:21220428]
HCA2 receptor in Human [GtoPdb: 312] [UniProtKB: Q8TDS4]
GtoPdb	-	-	2.8	pEC50	-	-	-

ChEMBL data shown on this page come from version 31:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]