darolutamide [Ligand Id: 10439] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| Androgen receptor in Human [GtoPdb: 628] [UniProtKB: P10275] | ||||||||
| GtoPdb | Antagonism of testosterone-induced activation of wtAR determined using AR-HEK293 cells and a luciferase reporter system. | - | 7.59 | pIC50 | 26 | nM | IC50 | Sci Rep (2015) 5: 12007 [PMID:26137992] |
| Androgen receptor in Rat [GtoPdb: 628] [UniProtKB: P15207] | ||||||||
| GtoPdb | Binding affinity measured in competition with [3H]mibolerone using wtAR isolated from rat ventral prostates. | - | 7.96 | pKi | 11 | nM | Ki | Sci Rep (2015) 5: 12007 [PMID:26137992] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
