PF-06873600 [Ligand Id: 10426] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| cyclin dependent kinase 2 in Human [GtoPdb: 1973] [UniProtKB: P24941] | ||||||||
| GtoPdb | Evaluated in a CDK2/Cyclin E1 mobility shift assay. | - | 9.92 | pKi | 0.12 | nM | Ki | WO2018033815A1. Pyridopyrimdinone cdk2/4/6 inhibitors. (2018) |
| cyclin dependent kinase 4 in Human [GtoPdb: 1976] [UniProtKB: P11802] | ||||||||
| GtoPdb | Evaluated in a CDK4/Cyclin D3 mobility shift assay. | - | 8.86 | pKi | 1.37 | nM | Ki | WO2018033815A1. Pyridopyrimdinone cdk2/4/6 inhibitors. (2018) |
| cyclin dependent kinase 6 in Human [GtoPdb: 1978] [UniProtKB: Q00534] | ||||||||
| GtoPdb | Evaluated in a CDK6/Cyclin D1 mobility shift assay. | - | 10.1 | pKi | 0.08 | nM | Ki | WO2018033815A1. Pyridopyrimdinone cdk2/4/6 inhibitors. (2018) |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
