HSD1590 [Ligand Id: 10424] activity data from GtoPdb

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  • Rho associated coiled-coil containing protein kinase 1 in Human [GtoPdb: 1503] [UniProtKB: Q13464]
Created with Highcharts 10.3.3ValuesChart context menuRho associated coiled-coil containing protein kinase 1pKd HumanpKi HumanpIC50 HumanpEC50 Human0246810Highcharts.com
  • Rho associated coiled-coil containing protein kinase 2 in Human [GtoPdb: 1504] [UniProtKB: O75116]
Created with Highcharts 10.3.3ValuesChart context menuRho associated coiled-coil containing protein kinase 2pKd HumanpKi HumanpIC50 HumanpEC50 Human0246810Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Rho associated coiled-coil containing protein kinase 1 in Human [GtoPdb: 1503] [UniProtKB: Q13464]
GtoPdb - - 8.78 pKd 1.65 nM Kd Eur J Med Chem (2019) 180: 449-456 [PMID:31330446]
GtoPdb - - 8.91 pIC50 1.22 nM IC50 Eur J Med Chem (2019) 180: 449-456 [PMID:31330446]
Rho associated coiled-coil containing protein kinase 2 in Human [GtoPdb: 1504] [UniProtKB: O75116]
GtoPdb - - 7.95 pKd 11.25 nM Kd Eur J Med Chem (2019) 180: 449-456 [PMID:31330446]
GtoPdb - - 9.29 pIC50 0.51 nM IC50 Eur J Med Chem (2019) 180: 449-456 [PMID:31330446]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.