GI‐530159 [Ligand Id: 10337] activity data from GtoPdb

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  • K2P2.1 in Human [GtoPdb: 514] [UniProtKB: O95069]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
K2P2.1 in Human [GtoPdb: 514] [UniProtKB: O95069]
GtoPdb Measuring GI‐530139-induced enhanced current via single hTREK1 channels measured at +60 mV in the inside‐out manual patch configuration, in a concentration–response experiment. - 6.05 pEC50 890 nM EC50 Br J Pharmacol (2018) 175: 2272-2283 [PMID:29150838]
GtoPdb Measuring 86Rb efflux by TREK1 induced by GI‐530159 at 70 mM potassium. - 6.12 pEC50 760 nM EC50 Br J Pharmacol (2018) 175: 2272-2283 [PMID:29150838]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.