ChEMBL ligand: CHEMBL395493 (spinorphin)
P2X3/P2X purinoceptor 3 in Human [ChEMBL: CHEMBL2998] [GtoPdb: 480] [UniProtKB: P56373] There should be some charts here, you may need to enable JavaScript!
FPR1 in Human [GtoPdb: 222] [UniProtKB: P21462] FPR1 in Mouse [GtoPdb: 222] [UniProtKB: P33766] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
P2X3/P2X purinoceptor 3 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2998] [GtoPdb: 480] [UniProtKB: P56373]
ChEMBL	Antagonist activity at human recombinant P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current in presence of 20 nM LVVYPWA peptide by two electrode voltage clamping technique	F	10.32	pIC50	0.05	nM	IC50	J Med Chem (2007) 50: 4543-4547 [PMID:17676725]
GtoPdb	-	-	11	pIC50	-	-	-
FPR1 in Human [GtoPdb: 222] [UniProtKB: P21462]
GtoPdb	-	-	4.3	pIC50	-	-	-	J Immunol (2001) 167: 6609-14 [PMID:11714831]; J Biol Chem (1992) 267: 7637-43 [PMID:1373134]
FPR1 in Mouse [GtoPdb: 222] [UniProtKB: P33766]
GtoPdb	-	-	3.9	pEC50	-	-	-	J Immunol (2001) 167: 6609-14 [PMID:11714831]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]