compound 1u [PMID: 30245402] [Ligand Id: 10258] activity data from GtoPdb

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  • Plasmodium falciparum histone deacetylase 1 in Plasmodium berghei [GtoPdb: 3072]
  • Plasmodium falciparum histone deacetylase 1 in Plasmodium falciparum 3D7 [GtoPdb: 3072] [UniProtKB: Q7K6A1]
  • Plasmodium falciparum histone deacetylase 1 in Plasmodium falciparum Dd2 [GtoPdb: 3072]
  • This target only has 0 pki data point
1 _lig_chart_1 Plasmodium falciparum histone deacetylase 1 Plasmodium bergheiPlasmodium falciparum 3D7Plasmodium falciparum Dd2
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Plasmodium falciparum histone deacetylase 1 in Plasmodium berghei [GtoPdb: 3072]
GtoPdb Parasite liver stage assay - 7.6 pIC50 25 nM IC50 Eur J Med Chem (2018) 158: 801-813 [PMID:30245402]
Plasmodium falciparum histone deacetylase 1 in Plasmodium falciparum 3D7 [GtoPdb: 3072] [UniProtKB: Q7K6A1]
GtoPdb Parasite growth inhibition assay - 8.4 pIC50 4 nM IC50 Eur J Med Chem (2018) 158: 801-813 [PMID:30245402]
Plasmodium falciparum histone deacetylase 1 in Plasmodium falciparum Dd2 [GtoPdb: 3072]
GtoPdb Parasite growth inhibition assay - 9 pIC50 1 nM IC50 Eur J Med Chem (2018) 158: 801-813 [PMID:30245402]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.