PQR620 [Ligand Id: 10142] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| mechanistic target of rapamycin kinase in Human [GtoPdb: 2109] [UniProtKB: P42345] | ||||||||
| GtoPdb | Binding affinity constant. | - | 9.57 | pKd | 0.27 | nM | Kd | J Med Chem (2018) 61: 10084-10105 [PMID:30359003] |
| GtoPdb | In vitro inhibition constant. | - | 7.97 | pKi | 10.8 | nM | Ki | J Med Chem (2018) 61: 10084-10105 [PMID:30359003] |
| phosphatidylinositol 3-kinase catalytic subunit type 3 in Human [GtoPdb: 2152] [UniProtKB: Q8NEB9] | ||||||||
| GtoPdb | - | - | 5.56 | pKd | 2750 | nM | Kd | J Med Chem (2018) 61: 10084-10105 [PMID:30359003] |
| phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha in Human [GtoPdb: 2153] [UniProtKB: P42336] | ||||||||
| GtoPdb | - | - | 6 | pKd | 1000 | nM | Kd | J Med Chem (2018) 61: 10084-10105 [PMID:30359003] |
| GtoPdb | - | - | 5.38 | pKi | 4203 | nM | Ki | J Med Chem (2018) 61: 10084-10105 [PMID:30359003] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
