KDM5 inhibitor N71 [Ligand Id: 10141] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| lysine demethylase 4A in Human [GtoPdb: 2675] [UniProtKB: O75164] | ||||||||
| GtoPdb | - | - | 5.28 | pIC50 | 5300 | nM | IC50 | J Med Chem (2018) 61: 10588-10601 [PMID:30392349] |
| lysine demethylase 5A in Human [GtoPdb: 2680] [UniProtKB: P29375] | ||||||||
| GtoPdb | AlphaLISA derived IC50 values of the inhibition of KDM5A-mediated histone demethylation. | - | 6.49 | pIC50 | 320 | nM | IC50 | J Med Chem (2018) 61: 10588-10601 [PMID:30392349] |
| lysine demethylase 5B in Human [GtoPdb: 2681] [UniProtKB: Q9UGL1] | ||||||||
| GtoPdb | AlphaLISA derived IC50 values of the inhibition of KDM5B-mediated histone demethylation. | - | 6.66 | pIC50 | 220 | nM | IC50 | J Med Chem (2018) 61: 10588-10601 [PMID:30392349] |
| lysine demethylase 6A in Human [GtoPdb: 2684] [UniProtKB: O15550] | ||||||||
| GtoPdb | - | - | 4.22 | pIC50 | >60000 | nM | IC50 | J Med Chem (2018) 61: 10588-10601 [PMID:30392349] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
