MDL-800 [Ligand Id: 10123] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| sirtuin 6 in Human [GtoPdb: 2712] [UniProtKB: Q8N6T7] | ||||||||
| GtoPdb | Binding of ligand to immobilised SIRT6 protein in a biolayer interferometry (Octet) assay. | - | 5.27 | pKd | 5400 | nM | Kd | Nat Chem Biol (2018) 14: 1118-1126 [PMID:30374165] |
| GtoPdb | FLUOR DE LYS® HDAC fluorometric activity assay measuring increased catalytic efficiency of SIRT6 deacetylation. | - | 4.99 | pEC50 | 10300 | nM | EC50 | Nat Chem Biol (2018) 14: 1118-1126 [PMID:30374165] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
