Dooku1 [Ligand Id: 10112] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| Piezo1 in Human [GtoPdb: 2945] [UniProtKB: Q92508] | ||||||||
| GtoPdb | Measuring antagonism of Yoda1-mediated calcium entry in HUVEC cells which endogenously express Piezo1 channels. | - | 5.82 | pIC50 | 1500 | nM | IC50 | Br J Pharmacol (2018) 175: 1744-1759 [PMID:29498036] |
| GtoPdb | Measuring antagonism of Yoda1-mediated calcium entry in HEK293 cells exogenously expressing human Piezo1 channels. | - | 5.89 | pIC50 | 1300 | nM | IC50 | Br J Pharmacol (2018) 175: 1744-1759 [PMID:29498036] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
