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Ligands
golimumab
golimumab
GtoPdb Ligand ID: 6776
Synonyms:
CNTO-148 | CNTO148 | Simponi®
golimumab is an
approved drug
(FDA (2009), EMA (2009))
Compound class:
Antibody
Comment:
TNFα inhibitor.
View more information in the IUPHAR Pharmacology Education Project:
golimumab
Summary
Biological activity
Clinical data
References
Immunopharmacology
Selectivity at ligand targets
Key to terms and symbols
Click column headers to sort
Target
Sp.
Type
Action
Value
Parameter
Concentration range (M)
Reference
tumour necrosis factor shed form
Hs
Antibody
Binding
10.7
pIC
50
-
2
⤷
pIC
50
10.7 (IC
50
1.8x10
-11
M) [
2
]
Description: Affinity for soluble TNFα measured by surface plasmon resonance