Synonyms: IL-1ra | interleukin-1 receptor antagonist protein | IRAP
Compound class:
Endogenous peptide in human, mouse or rat
Comment: A recombinant, non-glycosylated version of this protein is marketed as rheumatoid arthritis drug anakinra.
Species: Human
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Natural/Endogenous Targets | |||
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Enzymes Catalysing Reactions with this Compound as a Substrate or Product | ||||||||
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Selectivity at catalytic receptors | |||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Targets where the ligand is described in the comment field | |
Target | Comment |
Interleukin-1 receptor, type II | Decoy receptor that binds IL-1α (IL1A, P01583), IL-1β (IL1B, P01584) and IL-1 receptor antagonist (IL1RN, P18510). |