Synonyms: bisindolylmaleimide I | Gö6850 | GF 109203X
Compound class:
Synthetic organic
Comment: GF109203X is a potent, ATP-competitive PKC inhibitor [3].
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
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Bioactivity Comments |
We have mapped the data presented in [3] to the bovine PKC isoforms as the source of the resolved isoforms is unclear in the article. |
Selectivity at enzymes | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Ligand mentioned in the following text fields |
Alpha subfamily overview |